Nature Reviews Drug Discovery Agent Skill

Use when targeting Nature Reviews Drug Discovery (Nat.

Context cost
2.3k tokensestimated from the bundle, loaded when it triggers
Bundle
1 file · 9.1 kBtext throughout, nothing executable
Licence
MITthe author’s own terms
Last change
—no release on file
Servers it uses
Noneruns standalone

What it does

Use when targeting Nature Reviews Drug Discovery (Nat. Rev. Drug Discov.) or deciding whether a drug-discovery review or analysis fits this commissioned, authoritative review venue. Encodes the journal's fit, framing, evidence bar, house style, official-submission re-check, and desk-reject heuristics.

What this skill changes about the agent has not been set out here as a list. Its SKILL.md, shown below, says it in the author’s own words.

documentation

The skill itself

A skill is instructions the model reads, so you can see what you are getting: below is the start of its SKILL.md. The front matter loads with every session, the body loads when the skill triggers, and the whole file comes with the install.

SKILL.md9.1 kB · preview
--- name: nature-reviews-drug-discovery ---
6# Nature Reviews Drug Discovery (nature-reviews-drug-discovery)
7
8## Journal positioning
9
10Nature Reviews Drug Discovery is a Springer Nature title and the field-defining review journal for drug discovery and development. Its defining character is authoritative, commissioned synthesis: it publishes no primary research, and the great majority of content is solicited by the editors from leaders in pharmacology, medicinal chemistry, translational medicine, and pharma R&D strategy. The journal rewards reviews and analyses that frame where a therapeutic area, target class, or development paradigm stands and where it is heading — integrating mechanism, clinical evidence, pipeline landscape, and commercial and regulatory context — rather than narrow methodological updates. Readership spans academic pharmacologists, biotech and pharma scientists, clinicians, and investors. This skill is a **fit / venue-selection / re-framing** tool. It does not replace the journal's current official submission guidelines. Because most articles are commissioned, an unsolicited submission almost always begins with a pre-submission proposal. Before submitting, re-check the live author instructions on the Nature Reviews Drug Discovery site.
11
12## When to trigger
13
14- The author is preparing a commissioned or proposed review on a drug target, modality, therapeutic area, or aspect of pharma R&D and names this journal as the venue.
15- A manuscript synthesizes the state of drug discovery or development for a field — integrating biology, clinical data, and pipeline landscape — and the author is choosing between this journal and Nature Medicine, Nature Reviews Methods Primers, or Cell Reports Medicine.
16- The author has a primary-research drug-discovery study and needs to be redirected, because this journal publishes no original data.
17- The author needs the journal's commissioning norms, scope boundaries, and desk-reject criteria before drafting a proposal.
18
19## Scope & topic fit
20
21- Target and pathway reviews: the biology, druggability, and clinical translation of a target class — kinases, GPCRs, ion channels, epigenetic regulators, protein-protein interactions — across discovery and development.
22- Modality and platform reviews: small molecules, biologics, antibody-drug conjugates, cell and gene therapies, RNA therapeutics, PROTACs and targeted degraders, covering chemistry, delivery, and clinical maturity.
23- Therapeutic-area landscapes: oncology, immunology, neurology, metabolic and infectious disease — synthesizing mechanism, the development pipeline, and unmet need.
24- Drug discovery and development paradigms: AI/ML in discovery, translational biomarkers, clinical trial design innovation, drug repurposing, and the science of attrition and productivity.
This is a preview of SKILL.md. Download or install the skill to get the whole thing.
In the file
SKILL.md1,243 words
Files1
LicenceMIT
Why you can read it

Nothing in a skill executes. The client loads the text and the model follows it, so a skill can be audited the way a runbook is — by reading it.

What it costs in context

Skills are not billed by the call. They are paid for in context: every token the instructions occupy is a token your code, your diff and your conversation cannot use. Here is what this one takes and when it takes it.

≈90
always loaded
The name and description, so the model knows the skill exists and when to reach for it.
2,185
on trigger
The instruction body, read only when the skill fires.
1.1%
of a 200k window
Ten skills this size would take about 11% of the window before you open a file.
050k100k150k200k context window

2.3k tokens, estimated from the bundle at four bytes to the token, held for the rest of the session once it triggers. Middling. Fine to keep on in a project where you use it weekly, worth unloading in one where you never do.

Servers bill, skills cost

A server charges by the month. A skill charges once per session, in context, and then keeps charging it for as long as the session lives.

Before and after

The same question, put to the same model twice: once as it comes, and once with these instructions loaded.

No worked example has been published for this skill yet.

The procedure it runs

The procedure has not been set out here step by step. It is in the body of its SKILL.md: the start of it is shown above, and the whole file comes with the install.

Prose, not code

These steps are written for a model to follow, not executed by a runtime. It can still be told to skip one, and it will say so when it does.

Servers it uses

None. This skill calls no MCP servers at all.

Everything it needs is in the instructions, so it works in a project with nothing connected — the model reads the file and changes how it works with what it can already reach.

Its SKILL.md does not declare which tools it asks the agent for, so what it touches is whatever the instructions themselves ask for — read them before you install it.

What it asks for
Writes filesnot declared
Network accessnot declared

This SKILL.md carries no allowed-tools line, so neither is declared. A skill grants no permissions of its own — it can only ask for tools your client already has.

What it will not do

Every skill is narrow, and the useful ones say where they stop. These are the jobs this one is the wrong tool for.

What this skill is not for has not been published here. Nothing is implied by that: it is a section the author has not filled in.

What is in the bundle

1 file, 9.1 kB on disk. A bundle is text throughout: the instructions the model reads, plus the templates it fills in.

  • SKILL.md9.1 kB
What is not in it

No dependencies and nothing executable: a skill is text the agent reads, so the bundle is 1 file you can review in full before installing. The MIT licence covers the templates and examples as well as the instructions.

Install

Installing copies the bundle into your project. Nothing runs at install time — the files sit on disk until the model reads them.

# Nature Reviews Drug Discovery · 2.3k tokens when loaded · macOS, Linux mkdir -p .claude/skills && t=$(mktemp -d) && curl -fsSL -o "$t/bundle.tar.gz" https://mcprush.com/api/skills/nature-reviews-drug-discovery/bundle.tar.gz && tar -xzf "$t/bundle.tar.gz" -C "$t" && [ -d "$t/nature-reviews-drug-discovery" ] && { [ ! -e .claude/skills/nature-reviews-drug-discovery ] || { mv .claude/skills/nature-reviews-drug-discovery "$t/.previous" && echo "Previous copy moved to $t/.previous"; }; } && mv "$t/nature-reviews-drug-discovery" .claude/skills/ && echo "Installed .claude/skills/nature-reviews-drug-discovery"
On Windows, or any OS with Node 20+
npx mcprush@latest skill add brycewang-stanford/nature-reviews-drug-discovery

Windows PowerShell says 'running scripts is disabled on this system'? Run Set-ExecutionPolicy -Scope CurrentUser RemoteSigned once, or type npx.cmd instead of npx (codex.cmd, gemini.cmd, grok.cmd likewise). PowerShell 7 needs neither. Writes to .claude/skills/nature-reviews-drug-discovery/ in the current project. For every project instead, run mkdir -p ~/.claude/skills && t=$(mktemp -d) && curl -fsSL -o "$t/bundle.tar.gz" https://mcprush.com/api/skills/nature-reviews-drug-discovery/bundle.tar.gz && tar -xzf "$t/bundle.tar.gz" -C "$t" && [ -d "$t/nature-reviews-drug-discovery" ] && { [ ! -e ~/.claude/skills/nature-reviews-drug-discovery ] || { mv ~/.claude/skills/nature-reviews-drug-discovery "$t/.previous" && echo "Previous copy moved to $t/.previous"; }; } && mv "$t/nature-reviews-drug-discovery" ~/.claude/skills/ && echo "Installed ~/.claude/skills/nature-reviews-drug-discovery" (macOS, Linux) — or add --global to the npx line. The curl line replaces .claude/skills/nature-reviews-drug-discovery/ only after the download succeeds, so files left there by another skill of the same name, or by an older release, do not mix in. A copy already there is moved aside, not deleted, and the line prints where.

Which clients pick it up on their own

A skill is a folder of text. Most of these read a skills folder and pick it up without being told; the rest take the same folder another way — an upload in the app, a parameter on an API call — and then choose it by its description just the same.

Claude Code.claude/skills/
Claude DesktopCustomize › Skills
ChatGPTSkills › Create › Upload
Cursor.cursor/skills/
VS Code.github/skills/
Codex CLI.agents/skills/
Gemini CLI.gemini/skills/
Grok Build.grok/skills/
Microsoft CopilotSkills › Upload a skill
PerplexityComputer › Skills › Upload a skill
DeepSeek Harness.dsh/skills/
Zed.agents/skills/
Devin Desktop.devin/skills/
Windsurf (legacy).windsurf/skills/
OpenAI Agents SDKInstructions or sandbox Skills
HTTP / APIa request parameter
This release
Versionnot versioned
Publishedno release date on file
PriceFree
Referencebrycewang-stanford/nature-reviews-drug-discovery

Versions

Its author publishes no version number, so there is nothing here to pin to: what you install is the folder as it stands today. Instructions change more often than APIs do — a skill can be rewritten entirely without anything it depends on moving.

Pinning

Nothing to pin to: this skill carries no version number of its own. What you install is what the folder holds on the day you install it.

Reviews

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Who can post

Anybody with an account, one review each. It carries the version that was current when you wrote it, and the publisher may reply once.

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