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Folklore Clinical Variant Interpretation is installed from its publisher's own source and answers where it runs, so this marketplace is not in the path of a single call. There is no address here to send one to, and a panel that pretended otherwise would be showing you an answer we made up. Install it and call it from your own client — the Installation tab has the entry for each one.
What it does
Folklore MCP 2.0.0 provides ACMG/AMP germline variant classification, gene profiles, disease associations and scientific literature. Eleven public tools work without an account or API key. Add a Folklore API key as a Bearer header in the same MCP client to access eighteen additional tools for case discovery, approved source file browsing, analysis submission and tracking, original JSON/PDF results and six views of the original JSON, for 29 tools in total. Processing follows the selected account subscription limits or available credits. Connect with Streamable HTTP at https://api.helena.bio/folklore/v1/mcp. Setup: https://folklore.helena.bio/integrations/mcp
Quickstart
# 1 — add it to Claude Code
claude mcp add --scope user --transport http folklore-clinical-variant-interpretation-mcp https://api.helena.bio/folklore/v1/mcp
# 2 — ask your agent for something these tools do
# classify_germline_variant, search_variant_literature, get_publication_details and 8 more
Folklore Clinical Variant Interpretation costs nothing on mcprush: there is no plan to choose here, no cap to set and nothing mcprush can bill you for.
Where are you running it?
Every route below installs the same thing and ends at the same approval screen. Nothing here runs on your machine and nothing runs on ours: this server answers at its publisher’s own address, and what you install is the connection straight to it.
This is a public server: it answers at its publisher’s own address and this marketplace is not in the path. Claude Code registers it in one command; --scope user makes it available in every project. The transport below is http, as the publisher's own manifest declares it.
claude mcp add --scope user --transport http folklore-clinical-variant-interpretation-mcp https://api.helena.bio/folklore/v1/mcpReconnect, or start a new session, and the tools appear in the model’s tool list.
One config entry pointing straight at the publisher’s own address — this marketplace is not in the path, and nothing from this listing executes on your machine.
11 tools, with what each one reads, writes and reaches shown before you agree — the same list on every route above. Read the tool surface.
Tool surface
What the model actually sees. Descriptions are diffed on every release — see version history.
Classify one GRCh38 germline nuclear SNV or simple indel smaller than 50 bp under ACMG/AMP. Accepts genomic, coding or protein HGVS, coordinates, SPDI, rsID or a returned canonical key. Returns normalized identity, automated classification, applied criteria, ClinVar assertions, population frequencies, annotations and source provenance when available. Ambiguous input returns candidates for selectio
| Parameter | Type | Required | Notes |
|---|---|---|---|
| assembly | string | no | Reference genome assembly. Folklore currently accepts GRCh38 only. |
| query | string | yes | One germline nuclear SNV or simple indel to resolve and interpret; accepted forms include coordinates, genomic/coding/protein HGVS, SPDI, rsID, or a returned Folklore canonical_key in GRCh38:chrN:posi |
Resolve one GRCh38 germline variant and retrieve publications from the PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Returns match types, source links, corpus provenance and retrieval time.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| assembly | string | no | Reference genome assembly. Folklore currently accepts GRCh38 only. |
| query | string | yes | One germline nuclear SNV or simple indel to resolve before retrieving its literature; this is a variant identifier, not a natural-language question. Accepts a returned Folklore canonical_key in GRCh38 |
| question | no | Optional natural-language focus applied after the variant is resolved, such as a condition or evidence question; do not put the variant identifier here. | |
| limit | integer | no | Maximum number of publications to return, from 1 to 25. |
Retrieve one PMID from the PubMed-derived genetics corpus, including title, abstract, authors, journal, publication types, MeSH terms, gene and variant mentions, retraction status and PubMed/PMC links.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| pmid | string | yes | One PubMed identifier to look up in Folklore's current corpus, as 1 to 12 digits without a PMID prefix. |
Search the genetics Literature Corpus by question, PMID, DOI, PMCID, gene, variant, phenotype, HPO or OMIM concept. Known publication identifiers provide exact anchors. Returns ranked publications, match types, scores and source links.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| query | string | yes | Natural-language literature question or exact PMID, DOI, PMCID, gene, variant, phenotype, HPO, or OMIM query. Include every known publication identifier when comparing or finding related papers. |
| limit | integer | no | Maximum number of publications to return, from 1 to 25. |
| sort | string | no | Result ordering: relevance-ranked, newest publication first, or oldest publication first. |
| cursor | no | Opaque continuation cursor from the preceding response for the same query and sort order; omit for the first page. |
Retrieve Helena Good campaign, rules, manifest and MCP connection URLs.
Takes no parameters.
Find diseases associated with an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance, including conflicting and limited assertions.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| limit | integer | no | Maximum number of source assertions per page, from 1 to 50. |
| offset | integer | no | Zero-based assertion offset; use the returned nextOffset when present. |
| gene | string | yes | One public human gene symbol or HGNC identifier, for example BRCA1 or HGNC:1100. |
Find genes associated with an exact MONDO identifier or disease-name search. Returns ClinGen validity assertions with inheritance, source reports and snapshot provenance. Name searches can return multiple disease identities.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| limit | integer | no | Maximum number of source assertions per page, from 1 to 50. |
| offset | integer | no | Zero-based assertion offset; use the returned nextOffset when present. |
| disease | string | yes | One public disease name or exact MONDO identifier (MONDO: followed by seven digits). A name search may match multiple distinct diseases. |
Resolve a human gene symbol, previous symbol, alias, HGNC, Ensembl or NCBI Gene identifier. Returns exact, alias, ambiguous, not_found or withdrawn status with candidates and identity_snapshot_id. Use a selected HGNC gene_id and snapshot_id with get_gene_profile. Gene-plus-HGVS and variant expressions use classify_germline_variant.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| query | string | yes | One public gene symbol, previous symbol, alias, HGNC ID, Ensembl gene ID or NCBI Gene ID. |
Read the selected gene_id and immutable snapshot_id from resolve_gene. Returns overview, disease validity, dosage, mechanisms, transcripts, native assemblies, constraint, ClinVar summaries and consequences, expression, GWAS, phenotypes and protein/pathways with source assertions, coverage, count units and null values. get_gene_section supplies further pages. Live search_gene_literature is separate
| Parameter | Type | Required | Notes |
|---|---|---|---|
| gene_id | string | yes | Canonical HGNC gene_id returned by resolve_gene. Select an explicit candidate when resolution is ambiguous. |
| snapshot_id | string | yes | identity_snapshot_id returned by resolve_gene, or snapshot_id from the current gene profile. Restart resolution after snapshot_unavailable. |
Read a gene-profile section using gene_id, snapshot_id and its returned opaque cursor. Returns source records, assembly/release, coverage, totals, count units and provenance. snapshot_unavailable requires a fresh resolution/profile request.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| gene_id | string | yes | Canonical HGNC gene_id returned by resolve_gene. Select an explicit candidate when resolution is ambiguous. |
| snapshot_id | string | yes | identity_snapshot_id returned by resolve_gene, or snapshot_id from the current gene profile. Restart resolution after snapshot_unavailable. |
| section | string | yes | Source-qualified section from the current profile. Literature is a separate live capture; use search_gene_literature for it. |
| limit | integer | no | Maximum source records per page, from 1 to 50. Counts retain their original source unit. |
| cursor | no | Opaque next_cursor returned for this same gene, snapshot and section. Omit for its first page. |
Retrieve a live publication capture for a resolved gene_id and snapshot_id. Returns source links, match labels, capture time/hash, degradation and gene/snapshot/sort-bound cursors. This capture is separate from the immutable reference snapshot and contains no abstracts.
| Parameter | Type | Required | Notes |
|---|---|---|---|
| gene_id | string | yes | Canonical HGNC gene_id returned by resolve_gene. Select an explicit candidate when resolution is ambiguous. |
| snapshot_id | string | yes | identity_snapshot_id returned by resolve_gene, or snapshot_id from the current gene profile. Restart resolution after snapshot_unavailable. |
| limit | integer | no | Maximum publication records in one live discovery page, from 1 to 25. |
| sort | string | no | Discovery ordering. Keep the same sort for continuation pages. |
| cursor | no | Opaque next_cursor returned for this same gene, snapshot and sort. Omit for the first page. |
- Every tool — any call limit is its publisher’s, not ours
- No card, and mcprush charges nothing for it
- Runs at its publisher’s own address — this marketplace is not in the path
- Nothing to cap, because mcprush bills nothing
What counts against your monthly calls
| Tool | Unit | Calls used | Out of the allowance |
|---|
Nothing here is billable: mcprush charges nothing to install Folklore Clinical Variant Interpretation or to call it, at any volume.
Two independent axes, because powerful and malicious are different questions. The grade is threat only. The capability level is blast radius, and it is never a penalty on the grade — it is priced as one subtract-only term in the score, where you can see it.
| Term | Level | What it prices | Points |
|---|---|---|---|
| capability-exposure | minimal | capability blast radius (minimal) — client exposure if the model is manipulated | −0 |
| coverage-honesty | manifest | inspection depth (manifest) — how much of the target the scan could see | −4 |
What the scan could actually read
A grade is only as meaningful as its coverage, so the scanner publishes its own depth before it publishes its result.
The scan read each tool’s name, description, input schema and annotations exactly as the server listed them the last time it answered us; no code was reviewed. We ask the server again about once a month, and a list that changed is graded again.
The implementation source was not read — this reflects the declared tool metadata only.
Capability — what it could do if the model were manipulated
Tags derived from each tool’s schema and the implementation, not from what the tool calls itself. minimal is the level these add up to.
| Tool | Capability tags | Why the tag was assigned |
|---|---|---|
| classify_germline_variant | no tags | |
| search_variant_literature | no tags | |
| get_publication_details | no tags | |
| search_literature_corpus | no tags | |
| support_helena | no tags | |
| get_gene_disease_associations | no tags | |
| search_disease_genes | no tags | |
| resolve_gene | no tags | |
| get_gene_profile | no tags | |
| get_gene_section | no tags | |
| search_gene_literature | no tags |
Toxic-flow graph
The lethal trifecta, checked as a graph rather than as a checklist: untrusted input, a sensitive source and an external sink have to meet before there is a path worth worrying about.
The public result for this release does not print the flow graph, so there is nothing to show here. That is not the same as "no paths were found": what the scan did read is above, under coverage.
Supply chain and provenance
This is the first scan of this surface here, so there is nothing yet to compare it against.
Every result on this tab comes from one deterministic pass over the published package — offline, rule by rule, and auditable line by line above. Same methodology version, same bytes, same score.
Release history
This is an address its publisher runs: which release it serves is theirs to choose, so there is nothing here to pin. The history below is for reading; the current release on file is 2.0.0.
No release note was published with this version.
- The version this listing was on when mcprush began following its releases. The registry was not asked when it shipped, so this row carries no date.
One review per account, from a signed-in account that does not publish this listing. Nothing else is asked — you can say what you think before you install it. Publishers can reply once per review, and a review can be edited or deleted by whoever wrote it.
Any signed-in account that does not publish Folklore Clinical Variant Interpretation can review it, once — before installing it or after. A review from an account that has installed it is marked as one.
Nobody has reviewed this listing. The rating on the card is the mean of the reviews written here and nothing else, so there is no rating until somebody writes the first — which takes a signed-in account that does not publish it, and nothing else.